Mouse Monoclonal Antibody to EIF2AK3 | ProMab 30115 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to EIF2AK3

catalog :

30115

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5G5

The same clone is also sold as:

OriGene: AM06529SU-N
Abnova: MAB10632
Invitrogen: MA5-15705

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30115

Title :

Mouse Monoclonal Antibody to EIF2AK3

Species :

Human

Clone :

5G5;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

Immunogen :

Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Autophagy. 2008 Apr 1;4(3):364-7. ; 2. J Biol Chem. 2008 Jun 20;283(25):17020-9. ; 3. Hum Mol Genet. 2008 Oct 15;17(20):3254-62.

Type :

Monoclonal Antibody

MW :

125kDa

Aliases :

PEK; WRS; PERK; EIF2AK3