antibody

Mouse Monoclonal Antibody to CD86

30107

100μl

monoclonal

mouse

nonconjugated

1.B.3

The same clone is also sold as:

• MyBioSource: MBS831174
• Abnova: MAB10541
• Invitrogen: MA5-15697
• OriGene: AM06519SU-N

western blot, ELISA

Mouse Monoclonal Antibody to CD86

Human

1B3;

Mouse IgG1

100μl

4℃; -20℃ for long term storage

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.

Purified recombinant fragment of human CD86 expressed in E. Coli.

Ascitic fluid containing 0.03% sodium azide.

ELISA: 1/10000; WB: 1/500 - 1/2000

1. Clin Exp Allergy. 2009 Dec;39(12):1852-6. ; 2. Am J Hum Genet. 2009 Nov;85(5):628-42. ; 3. Immunology. 2009 Nov;128(3):334-41.

Monoclonal Antibody

52kDa

B70; B7-2; LAB72; CD28LG2; MGC34413; CD86