Mouse Monoclonal Antibody to UBE1L | ProMab 30095 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to UBE1L

catalog :

30095

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5B10

The same clone is also sold as:

OriGene: AM06505SU-N
Abnova: MAB10343
Invitrogen: MA5-15685

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30095

Title :

Mouse Monoclonal Antibody to UBE1L

Species :

Human

Clone :

5B10;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The modification of proteins with ubiquitin is an important cellular mechanism for targeting.Tissue specificity: Expressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

Immunogen :

Purified recombinant fragment of human UBE1L expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Cancer Res. 1992 Mar 15;52(6):1536-41 ; 2. Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6071-5. ; 3. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3806-11.

Type :

Monoclonal Antibody

MW :

112kDa

Aliases :

D8; UBE2; UBA1B; UBE1L; MGC12713; UBA7