Mouse Monoclonal Antibody to HK1 | ProMab 30084 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to HK1

catalog :

30084

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

'7A7

The same clone is also sold as:

Bio-Rad: VMA00230
OriGene: AM06493SU-N
Abnova: MAB10682
Invitrogen: MA5-15675
Novus Biologicals: NBP1-51639

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

Catalog :

30084

Title :

Mouse Monoclonal Antibody to HK1

Species :

Human; Rat; Mouse

Clone :

7A7;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.

Immunogen :

Purified recombinant fragment of human HK1 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000

References :

1. Cell. 2005 Sep 23;122(6):957-68. ; 2. J Biomed Sci. 2007 Mar;14(2):195-202. ; 3. J Neural Transm. 2009 Mar;116(3):275-89.

Type :

Monoclonal Antibody

MW :

102kDa

Aliases :

HKI; HXK1; HK1-ta; HK1-tb; HK1-tc; HK1