Mouse Monoclonal Antibody to NFKBIB | ProMab 30082 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to NFKBIB

catalog :

30082

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7B4

The same clone is also sold as:

Invitrogen: MA5-15673
Cell Signaling Technology: 8635
OriGene: AM06491SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30082

Title :

Mouse Monoclonal Antibody to NFKBIB

Species :

Human

Clone :

7B4;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.

Immunogen :

Purified recombinant fragment of human NFKBIB expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Mol Cell Biol. 2004 Apr;24(7):3048-56. ; 2. J Biol Chem. 2004 Oct 15;279(42):44030-8. ; 3. J Bone Miner Res. 2009 Dec;24(12):2039-49.

Type :

Monoclonal Antibody

MW :

45kDa

Aliases :

IKBB; TRIP9; NFKBIB