Mouse Monoclonal Antibody to STAT5B | ProMab 30074 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to STAT5B

catalog :

30074

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5B3

The same clone is also sold as:

Invitrogen: MA5-15665
Bio-Rad: VMA00229
OriGene: AM06481SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30074

Title :

Mouse Monoclonal Antibody to STAT5B

Species :

Human

Clone :

5B3;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Immunogen :

Purified recombinant fragment of human STAT5B expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide. ; ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Mol Cancer. 2009 Aug 26;8:67. ; 2. Bone. 2010 Feb;46(2):524-33.

Type :

Monoclonal Antibody

MW :

90kDa

Aliases :

STAT5; STAT5B