Mouse Monoclonal Antibody to WDR5 | ProMab 30073 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to WDR5

catalog :

30073

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7B11

The same clone is also sold as:

Invitrogen: MA5-15664
OriGene: AM06480SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30073

Title :

Mouse Monoclonal Antibody to WDR5

Species :

Human

Clone :

7B11;

lsotype :

Mouse IgG2b

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.

Immunogen :

Purified recombinant fragment of human WDR5 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Mol Syst Biol. 2007;3:89. ; 2. J Biol Chem. 2008 Nov 21;283(47):32162-75.

Type :

Monoclonal Antibody

MW :

36.6kDa

Aliases :

SWD3; BIG-3; WDR5