Mouse Monoclonal Antibody to FLT4 | ProMab 30060 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to FLT4

catalog :

30060

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4H4

The same clone is also sold as:

Invitrogen: MA5-15651
OriGene: AM06464SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30060

Title :

Mouse Monoclonal Antibody to FLT4

Species :

Human

Clone :

4H4;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. Tissue specificity: Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain. VEGFR-3 is induced in all endothelial cells (EC’s) during early embryogenesis, and its expression eventually disappears from the vascular endothelial cells of adult tissues. VEGFR-3 is constitutively expressed in the adult lymphatic endothelium. Although VEGFR-3 is not expressed in adult blood vessels, it is induced in vascular endothelial cells of tumor-bearing tissues.VEGFR-3 expression in adults is largely restricted to the endothelial cells of the lymphatic system, and high endothelial venules (HEV).

Immunogen :

Purified recombinant fragment of human FLT4 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Prostate. 2009 Jun 15;69(9):982-90. ; 2. J Cell Sci. 2009 Sep 15;122(Pt 18):3358-64. ; 3. Oncol Rep. 2009 Nov;22(5):1093-100.

Type :

Monoclonal Antibody

MW :

145kDa

Aliases :

PCL; FLT41; LMPH1A; VEGFR3; FLT4