Mouse Monoclonal Antibody to NME1 | ProMab 30051 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to NME1

catalog :

30051

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4B2

The same clone is also sold as:

Invitrogen: MA5-15642
Abnova: MAB10833
Novus Biologicals: NBP1-47398
OriGene: AM06451SU-N

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30051

Title :

Mouse Monoclonal Antibody to NME1

Species :

Human

Clone :

4B2;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

non-metastatic cells 1,protein,with a nm23 nucleoside diphosphate kinase gene family,involved in the phosphorylation of nucleoside diphosphates,with a reduced expression in tumor progression to the metastatic phenotype,mutated in agressive neuroblastoma,expressed in lung carcinoma cell lines not in normal lung,pyrimidine biosynthetic pathway. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. Has tumor metastasis-suppressive capacity.Tissue specificity: Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.

Immunogen :

Purified recombinant fragment of human NME1 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. J Cell Biochem. 2009 Mar 1;106(4):666-72. ; 2. FEBS Lett. 2009 Sep 3;583(17):2789-92. ; 3. PLoS One. 2009 Nov 23;4(11):e7949.

Type :

Monoclonal Antibody

MW :

17kDa

Aliases :

NB; AWD; NBS; GAAD; NM23; NDPKA; NDPK-A; NM23-H1; NME1