Mouse Monoclonal Antibody to SNAI2 | ProMab 30037 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to SNAI2

catalog :

30037

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2H5

The same clone is also sold as:

OriGene: AM06436SU-N
Invitrogen: MA5-15628

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30037

Title :

Mouse Monoclonal Antibody to SNAI2

Species :

Human

Clone :

2H5;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in γ-irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Immunogen :

Purified recombinant fragment of human SNAI2 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Biochem J. 2008 Dec 1;416(2):179-87. ; 2. Mol Biol Cell. 2008 Nov;19(11):4875-87. ; 3. Am J Pathol. 2009 Jun;174(6):2107-15.

Type :

Monoclonal Antibody

MW :

30kDa

Aliases :

SLUG; WS2D; SLUGH1; MGC10182; SNAI2