Mouse Monoclonal Antibody to ZBTB7B | ProMab 30011 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to ZBTB7B

catalog :

30011

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7C12

The same clone is also sold as:

OriGene: AM06405SU-N
Invitrogen: MA5-15602
Abnova: MAB10350

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

Catalog :

30011

Title :

Mouse Monoclonal Antibody to ZBTB7B

Species :

Human

Clone :

7C12;

lsotype :

Mouse lgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Immunogen :

Purified recombinant fragment of human ZBTB7B expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000

References :

1.Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9372-6. ; 2.J Biol Chem. 2000 Sep 1;275(35):27421-38. ; 3.J Cell Biochem. 2009 Aug 15;107(6):1037-45. Review.

Type :

Monoclonal Antibody

MW :

58kDa

Aliases :

THPOK; ZFP67; ZBTB15; c-Krox; hcKrox; ZNF857B; DKFZp686G01254; ZBTB7B