Mouse Monoclonal Antibody to MAP2K2 | ProMab 30009 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MAP2K2

catalog :

30009

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7F5

The same clone is also sold as:

OriGene: AM06400SU-N
Invitrogen: MA5-15600
Abnova: MAB10792

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, flow cytometry

product information

Catalog :

30009

Title :

Mouse Monoclonal Antibody to MAP2K2

Species :

Human; Mouse; Rat

Clone :

7F5;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

MAP2K2, also called MEK2, it is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax.

Immunogen :

Purified recombinant fragment of human MAP2K2 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. Mol Cell Biol. 1993 Aug;13(8):4679-90. ; 2. Eur J Biochem. 1995 Nov 15;234(1):32-8. ; 3. Oncogene. 1998 Jul 9;17(1):57-65.

Type :

Monoclonal Antibody

MW :

44kDa

Aliases :

MEK2; MKK2; MAPKK2