Mouse Monoclonal Antibody to AKT2 | ProMab 30002 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to AKT2

catalog :

30002

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1B6

The same clone is also sold as:

Abnova: MAB15183
Invitrogen: MA5-15593
OriGene: AM06381SU-N

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

Catalog :

30002

Title :

Mouse Monoclonal Antibody to AKT2

Species :

Human; Rat; Monkey

Clone :

1B6;

lsotype :

Mouse IgG2b

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.

Immunogen :

Purified recombinant fragment of human AKT2 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000

References :

1. Am J Physiol Endocrinol Metab. 2004 Jul;287(1):E8-E15. ; 2. Oncol Rep. 2004 Jan;11(1):25-32. ; 3. Cancer Res. 2003 Jan 1;63(1):196-206.

Type :

Monoclonal Antibody

MW :

60kDa

Aliases :

PKBB; PRKBB; PKBBETA; RAC-BETA