Mouse Monoclonal Antibody to HDAC4 | ProMab 20423 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to HDAC4

catalog :

20423

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7B2

The same clone is also sold as:

Invitrogen: MA5-15580
OriGene: AM06461SU-N
Bio-Rad: VMA00289

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20423

Title :

Mouse Monoclonal Antibody to HDAC4

Species :

Human

Clone :

7B2;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Immunogen :

Purified recombinant fragment of human HDAC4 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Biochem Biophys Res Commun. 2008 Dec 19;377(3):852-6. ; 2. Curr Top Med Chem. 2009;9(3):235-40. ; 3. Nucleic Acids Res. 2010 May;38(9):2813-24.

Type :

Monoclonal Antibody

MW :

119kDa

Aliases :

HD4; HDACA; HA6116; HDAC-A; KIAA0288; HDAC4