Mouse Monoclonal Antibody to BMP4 | ProMab 20415 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to BMP4

catalog :

20415

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10F4B4

The same clone is also sold as:

Invitrogen: MA5-15572
Abnova: MAB10507
OriGene: AM06396SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20415

Title :

Mouse Monoclonal Antibody to BMP4

Species :

Human

Clone :

10F4B4;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

Immunogen :

Purified recombinant fragment of human BMP4 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Genomics. 1995 Jun 10;27(3):559-60. ; 2. DNA Seq. 1995;5(5):273-5. ; 3. J Bone Miner Res. 2009 Dec;24(12):2039-49. ; 4. Stem Cells Dev. 2009 Nov;18(9):1283-92.

Type :

Monoclonal Antibody

MW :

64kDa

Aliases :

ZYME; BMP2B; OFC11; BMP2B1; MCOPS6; BMP4