Mouse Monoclonal Antibody to KRT15 | ProMab 20410 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to KRT15

catalog :

20410

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6E7

The same clone is also sold as:

Invitrogen: MA5-15567
OriGene: AM06387SU-N
Abnova: MAB10723

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

20410

Title :

Mouse Monoclonal Antibody to KRT15

Species :

Human

Clone :

6E7;

lsotype :

Mouse IgG2a

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.

Immunogen :

Purified recombinant fragment of KRT15 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. J Invest Dermatol. 1999. 112(3):362-9 ; 2. Exp Cell Res. 2006. 254(1):80-90 ; 3. Mol Cell Biol. 2000. 24(8):3168-79

Type :

Monoclonal Antibody

MW :

49kDa

Aliases :

K15; CK15; K1CO; KRT1