Mouse Monoclonal Antibody to AFP | ProMab 20405 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to AFP

catalog :

20405

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6 E6

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20405

Title :

Mouse Monoclonal Antibody to AFP

Species :

Human

Clone :

6E6;

lsotype :

Mouse IgG2b

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Immunogen :

Purified recombinant fragment of human AFP expressed in E. Coli.

Formulation :

Antibody are purified by protein G affinity chromatography. ; Liquid in PBS containing 50% glycerol and 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Proc Natl Acad Sci U S A. 1985 Nov;82(21):7160-4. ; 2. Pediatr Hematol Oncol. 2001 Dec;18(8):509-18. ; 3. Tumour Biol. 2002 Jul-Aug;23(4):202-11.

Type :

Monoclonal Antibody

MW :

69kDa

Aliases :

alpha-fetoprotein; FETA; HPAFP