Mouse Monoclonal Antibody to ROR1 | ProMab 20372 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to ROR1

catalog :

20372

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2H6

The same clone is also sold as:

OriGene: AM06399SU-N
Boster: M03192
MyBioSource: MBS850362
Invitrogen: MA5-15539
Abnova: MAB10314

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

product information

Catalog :

20372

Title :

Mouse Monoclonal Antibody to ROR1

Species :

Human

Clone :

2H6;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

ROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases.

Immunogen :

Recombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000

References :

1. J Cell Sci. 2005 Jan 15;118(Pt 2):433-46. ; 2. Oncogene. 1996 Oct 3;13(7):1555-9.

Type :

Monoclonal Antibody

MW :

101kDa

Aliases :

ROR1