Mouse Monoclonal Antibody to CD40 | ProMab 20366 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CD40

catalog :

20366

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9G10

The same clone is also sold as:

Abnova: MAB10537
OriGene: AM06355SU-N
Invitrogen: MA5-15535

reactivity :

human

application :

immunocytochemistry

product information

Catalog :

20366

Title :

Mouse Monoclonal Antibody to CD40

Species :

Human

Clone :

9G10;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

CD40 molecule, TNF receptor superfamily member 5. It is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Immunogen :

Purified recombinant fragment of CD40 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; ICC: 1/200 - 1/1000

References :

1. Clin Cancer Res. 2003 Feb;9(2):722-8. ; 2. Clin Cancer Res. 2003 Feb;9(2):619-24. ; 3. Immunity. 1999 Sep;11(3):339-48.

Type :

Monoclonal Antibody

Aliases :

p50; Bp50; CDW40; TNFRSF5