Mouse Monoclonal Antibody to AGT | ProMab 20360 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to AGT

catalog :

20360

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1B1

The same clone is also sold as:

Abnova: MAB10442
Invitrogen: MA5-15531
OriGene: AM06351SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20360

Title :

Mouse Monoclonal Antibody to AGT

Species :

Human

Clone :

1B1;

lsotype :

Mouse IgG2b

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Immunogen :

Purified recombinant fragment of human AGT expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1900-7. ; 2. Regul Pept. 2006 Jan 15;133(1-3):155-9.

Type :

Monoclonal Antibody

MW :

53kDa

Aliases :

ANHU