Mouse Monoclonal Antibody to FGFR1 | ProMab 20359 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to FGFR1

catalog :

20359

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3D4F7

The same clone is also sold as:

Invitrogen: MA5-15530
OriGene: AM06350SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20359

Title :

Mouse Monoclonal Antibody to FGFR1

Species :

Human

Clone :

3D4F7;

lsotype :

Mouse IgG2b

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome. It is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.

Immunogen :

Purified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. J Biol Chem. 2004 Jul 9;279(28):29325-35. ; 2. Arterioscler Thromb Vasc Biol. 2005 May;25(5):944-9. ; 3. Breast Cancer Res. 2007;9(2):R23.

Type :

Monoclonal Antibody

MW :

92kDa

Aliases :

CEK; FLG; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; HBGFR