Mouse Monoclonal Antibody to PDGFRβ | ProMab 20358 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PDGFRβ

catalog :

20358

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1.A.2

The same clone is also sold as:

OriGene: AM06349SU-N
Invitrogen: MA5-15529
MyBioSource: MBS850789

reactivity :

human, mouse

application :

western blot, ELISA

product information

Catalog :

20358

Title :

Mouse Monoclonal Antibody to PDGFRβ

Species :

Human, Mouse

Clone :

1A2;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Platelet-derived growth factor receptor, beta polypeptide, also known as PDGFRB, PDGFRβ or CD140B. It is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. This family exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor α (PDGFRα) and PDGF receptor β (PDGFRβ). These growth factors are mitogens for cells of mesenchymal origin. PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Immunogen :

Purified recombinant fragment of human PDGFRβ expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Biochem Biophys Res Commun. 1997 Jun 27;235(3):455-60. ; 2. Hum Pathol. 2005 Mar;36(3):242-9. ; 3. J Virol. 2007 May;81(10):5112-20.

Type :

Monoclonal Antibody

MW :

190kDa

Aliases :

JTK12; PDGFR; CD140B; PDGFR1; PDGFRB