Mouse Monoclonal Antibody to CD18 | ProMab 20346 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CD18

catalog :

20346

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10E12

The same clone is also sold as:

Abnova: MAB10423
Invitrogen: MA5-15517
OriGene: AM06337SU-N

reactivity :

human, mouse

application :

immunocytochemistry

product information

Catalog :

20346

Title :

Mouse Monoclonal Antibody to CD18

Species :

Human, Mouse

Clone :

10E12;

lsotype :

Mouse IgG2b

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

Immunogen :

Purified recombinant fragment of CD18 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; ICC: 1/200 - 1/1000

References :

1. Microcirculation. 2008 Aug;15(6):555-67. ; 2. Mol Immunol. 2008 Feb;45(3):709-18. ; 3. J Biol Chem. 2007 Aug 17;282(33):24310-9.

Type :

Monoclonal Antibody

MW :

85kDa

Aliases :

LAD; MF17; LCAMB; LFA-1; ITGB2