Mouse Monoclonal Antibody to TrkA | ProMab 20337 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to TrkA

catalog :

20337

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6B2

The same clone is also sold as:

Invitrogen: MA5-15509
OriGene: AM06329SU-N
Abnova: MAB10431

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

product information

Catalog :

20337

Title :

Mouse Monoclonal Antibody to TrkA

Species :

Human

Clone :

6B2;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

TrkA, also known as NTRK1, MTC, TRK, TRK1. It is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Immunogen :

Purified recombinant extracellular fragment of human TrkA (aa33-423) fused with hIgGFc tag expressed in HEK293 cell line.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000

References :

1. DNA Repair (Amst). 2008 Oct 1;7(10):1757-64. ; 2. Traffic. 2008 Jul;9(7):1146-56.

Type :

Monoclonal Antibody

MW :

87.4kDa

Aliases :

NTRK1, MTC, TRK, TRK1