Mouse Monoclonal Antibody to AXL | ProMab 20332 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to AXL

catalog :

20332

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7E10

The same clone is also sold as:

Bio-Rad: VMA00320
OriGene: AM06326SU-N
Invitrogen: MA5-15504

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

product information

Catalog :

20332

Title :

Mouse Monoclonal Antibody to AXL

Species :

Human

Clone :

7E10;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

AXL: AXL receptor tyrosine kinase, also known as UFO, JTK11. Entrez Protein NP_001690. It is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen :

Purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000

References :

1. Br J Cancer. 2006 May 22;94(10):1446-51. ; 2. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5799-804.

Type :

Monoclonal Antibody

MW :

97.4kDa

Aliases :

UFO; JTK11