antibody

Mouse Monoclonal Antibody to Cytokeratin 5

20322

100μl

monoclonal

mouse

nonconjugated

1E1

The same clone is also sold as:

• Invitrogen: MA5-15494
• Abnova: MAB10728
• OriGene: AM06316SU-N

western blot, ELISA

Mouse Monoclonal Antibody to Cytokeratin 5

Human

1E1;

Mouse IgG1

100μl

4℃; -20℃ for long term storage

Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.

Purified recombinant fragment of Cytokeratin 5 expressed in E. Coli. ;

Ascitic fluid containing 0.03% sodium azide. ;

ELISA: 1/10000; WB: 1/500 - 1/2000

1. J Invest Dermatol. 2003 Sep;121(3):482-5. ; 2. J Cell Sci. 2005 Mar 1;118(Pt 5):1081-90.

Monoclonal Antibody

62.3kDa

K5; CK5; KRT5A; KRT5