Mouse Monoclonal Antibody to FGR | ProMab 20318 product information

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to FGR

catalog :

20318

quantity :

100μl

price :

352.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

#6G2

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry

more info or order :

ProMab product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 7	Freedman T, Tan Y, Skrzypczynska K, Manz B, Sjaastad F, Goodridge H, et al. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. elife. 2015;4: pubmed publisher

product information

Catalog :

20318

Title :

Mouse Monoclonal Antibody to FGR

Species :

Human,Mouse

Clone :

6G2;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Immunogen :

Purified recombinant fragment of human FGR expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Immunity. 2005 Feb;22(2):235-46. ; 2. Biochemistry. 2007 Oct 2;46(39):11023-32.

List Price (USD) :

352.00 USD

Type :

Monoclonal Antibody

MW :

56kDa

Aliases :

SRC2; c-fgr; c-src2; p55c-fgr; p58c-fgr

more info or order :

ProMab product webpage