Mouse Monoclonal Antibody to CHIT1 | ProMab 20302 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CHIT1

catalog :

20302

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D9G2

The same clone is also sold as:

Abnova: MAB10472

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20302

Title :

Mouse Monoclonal Antibody to CHIT1

Species :

Human

Clone :

1D9G2;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

Immunogen :

Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Sarcoidosis Vasc Diffuse Lung Dis. 2007 Mar;24(1):59-64. ; 2. Clin Biochem. 2007 Mar;40(5-6):365-9.

Type :

Monoclonal Antibody

Aliases :

Chitotriosidase;CHI3; CHIT; FLJ00314; MGC125322; CHIT1