This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ProMab
product type :
antibody
product name :
Mouse Monoclonal Antibody to PEG10
catalog :
20296
quantity :
100μl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4C10A7

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
product information
Catalog :
20296
Title :
Mouse Monoclonal Antibody to PEG10
Species :
Human
Clone :
4C10A7;
lsotype :
Mouse IgG1
Size :
100μl
Storage :
4℃; -20℃ for long term storage
Description :
PEG10, paternally expressed 10. The PEG10 includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.
Immunogen :
Purified recombinant fragment of human PEG10 expressed in E. Coli.
Formulation :
Ascitic fluid containing 0.03% sodium azide. ;
Applications :
ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
References :
1. Oncogene. 2007 Aug 23;26(39):5741-51. ; 2. FEBS Lett. 2008 Aug 6;582(18):2793-8.
Type :
Monoclonal Antibody
MW :
Isoform RF1 (37kDa); RF1/RF2 (80kDa)
Aliases :
Edr; HB-1; Mar2; MEF3L; Mart2; RGAG3
company information
ProMab
5221 Central Avenue, Suite 200
Richmond, CA 94804
info@promab.com
http://www.promab.com
1-866-339-0871
headquarters: USA