Mouse Monoclonal Antibody to ETV1 | ProMab 20281 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to ETV1

catalog :

20281

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1C8B6

The same clone is also sold as:

Invitrogen: MA5-15461
Abnova: MAB10589
OriGene: AM06285SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20281

Title :

Mouse Monoclonal Antibody to ETV1

Species :

Human

Clone :

1C8B6;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.

Immunogen :

Purified recombinant fragment of ETV1 (aa1-191) expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Neoplasia. 2006 Oct;8(10):826-32. ; 2. Cancer Genet Cytogenet. 2008 May;183(1):21-7.

Type :

Monoclonal Antibody

Aliases :

ER81