Mouse Monoclonal Antibody to Cytokeratin 8 | ProMab 20280 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to Cytokeratin 8

catalog :

20280

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8A5D12

The same clone is also sold as:

Abnova: MAB10601
Invitrogen: MA5-15460
OriGene: AM06284SU-N

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

Catalog :

20280

Title :

Mouse Monoclonal Antibody to Cytokeratin 8

Species :

Human

Clone :

8A5D12;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Immunogen :

Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000

References :

1. Cancer Genet Cytogenet. 2007 Oct 15;178(2):94-103. ; 2. Cancer Lett. 2008 Jul 8;265(2):188-96.

Type :

Monoclonal Antibody

MW :

54kDa

Aliases :

CK8; CYK8; K2C8; KRT8