Mouse Monoclonal Antibody to EP300 | ProMab 20261 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to EP300

catalog :

20261

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7D8A6

The same clone is also sold as:

OriGene: AM06269SU-N
Invitrogen: MA5-15444

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20261

Title :

Mouse Monoclonal Antibody to EP300

Species :

Human

Clone :

7D8A6;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

Immunogen :

Purified recombinant fragment of EP300 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. J Biol Chem. 2007 Mar 30;282(13):9678-87. ; 2. Mol Cell Biol. 2008 Feb;28(4):1383-92.

Type :

Monoclonal Antibody

Aliases :

p300; KAT3B