This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ProMab
product type :
antibody
product name :
Mouse Monoclonal Antibody to HDAC3
catalog :
20259
quantity :
100μl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7G6C5
The same clone is also sold as:
The same clone is also sold as:
- Abnova: MAB12608
- OriGene: AM06267SU-N
- Invitrogen: MA5-15442
- Cell Signaling Technology: 3949
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
product information
Catalog :
20259
Title :
Mouse Monoclonal Antibody to HDAC3
Species :
Human
Clone :
7G6C5;
lsotype :
Mouse IgG2a
Size :
100μl
Storage :
4℃; -20℃ for long term storage
Description :
HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Immunogen :
Purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli.
Formulation :
Ascitic fluid containing 0.03% sodium azide.
Applications :
ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000
References :
1. Folia Biol (Praha). 2006;52(1-2):21-33. ; 2. Mol Cell Biol. 2007 Feb;27(4):1280-95. ; 3. Mol Carcinog. 2008 Feb;47(2):137-47.
Type :
Monoclonal Antibody
MW :
48.8kDa
Aliases :
HD3; RPD3; RPD3-2
company information
ProMab
5221 Central Avenue, Suite 200
Richmond, CA 94804
Richmond, CA 94804
info@promab.com
http://www.promab.com1-866-339-0871
headquarters: USA
questions and comments