Mouse Monoclonal Antibody to PARL | ProMab 20241 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PARL

catalog :

20241

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8C4B2

The same clone is also sold as:

OriGene: AM06254SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20241

Title :

Mouse Monoclonal Antibody to PARL

Species :

Human

Clone :

8C4B2;

lsotype :

Mouse IgG2b

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen :

Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. J Alzheimers Dis. 2001 Apr;3(2):181-190. ; 2. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. ; 3. Nature. 2003 May 29;423(6939):537-41.

Type :

Monoclonal Antibody

Aliases :

PSARL; PSARL1; RHBDS1