This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ProMab
product type :
antibody
product name :
Mouse Monoclonal Antibody to PAR4
catalog :
20213
quantity :
100μl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3G9H7

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
product information
Catalog :
20213
Title :
Mouse Monoclonal Antibody to PAR4
Species :
Human
Clone :
3G9H7;
lsotype :
Mouse IgG1
Size :
100μl
Storage :
4℃; -20℃ for long term storage
Description :
Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.
Immunogen :
Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli. ;
Formulation :
Ascitic fluid containing 0.03% sodium azide.
Applications :
ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
References :
1. J Biol Chem. 2004 Jul 2;279(27):28266-75. ; 2. Exp Hematol. 2004 Jul;32(7):649-56. ; 3. Mol Cell Biol. 2005 Feb;25(3):1146-61. ; 4. Psychiatr Genet. 2006 Oct;16(5):193-6.
Type :
Monoclonal Antibody
Aliases :
PAWR
company information
ProMab
5221 Central Avenue, Suite 200
Richmond, CA 94804
info@promab.com
http://www.promab.com
1-866-339-0871
headquarters: USA