Mouse Monoclonal Antibody to MSH6 | ProMab 20192 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MSH6

catalog :

20192

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3A10H7

The same clone is also sold as:

Invitrogen: MA5-15392
OriGene: AM06411SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20192

Title :

Mouse Monoclonal Antibody to MSH6

Species :

Human

Clone :

3A10H7;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.

Immunogen :

Purified recombinant fragment of MSH6 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Oncology (Williston Park). 2005 Apr;19(4):455-63. ; 2. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):558-63.

Type :

Monoclonal Antibody

Aliases :

GTBP; HSAP; HNPCC5