Mouse Monoclonal Antibody to Survivin | ProMab 20176 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to Survivin

catalog :

20176

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2H5H2

The same clone is also sold as:

Santa Cruz Biotechnology: sc-101433
Invitrogen: MA5-17184
Abnova: MAB10414
OriGene: AM06207SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20176

Title :

Mouse Monoclonal Antibody to Survivin

Species :

Human

Clone :

2H5H2;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

Immunogen :

Purified recombinant fragment of Survivin expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Urology. 2007 Sep;70(3):482-6. ; 2. World J Gastroenterol. 2007 May 28;13(20):2784-90. ; 3. Histopathology. 2007 Jun;50(7):835-42.

Type :

Monoclonal Antibody

Aliases :

API4; EPR-1; BIRC5