Mouse Monoclonal Antibody to BNP | ProMab 20157 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to BNP

catalog :

20157

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9H6B4

The same clone is also sold as:

OriGene: AM06192SU-N
MyBioSource: MBS850376
Abnova: MAB10510

reactivity :

human

application :

immunohistochemistry

product information

Catalog :

20157

Title :

Mouse Monoclonal Antibody to BNP

Species :

Human

Clone :

9H6B4;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.

Immunogen :

Synthetic peptide corresponding to aa (Gly-Leu-Gln-Glu-Gln-Arg-Asn-His-Leu-Gln-Gly-Lys-Leu-Cys) of human BNP, conjugated to KLH.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; IHC: 1/200 - 1/1000

References :

1. Dawson A. Struthers AD. Expert Opin Biol Ther. 2003, Feb, 3(1):107-12. Review. ; 2. Pfister R. Erdmann E. Schneider CA. Dtsch Med Wochenschr. 2003,May 2, 128(18):1007-12. ;

Type :

Monoclonal Antibody

Aliases :

BNP; NPPB