Mouse Monoclonal Antibody to MER | ProMab 20153 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MER

catalog :

20153

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7E5G1

The same clone is also sold as:

OriGene: AM06188SU-N
Invitrogen: MA5-15358

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20153

Title :

Mouse Monoclonal Antibody to MER

Species :

Human

Clone :

7E5G1;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. MER has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S have been identified as ligands for the UFO family of receptors. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Immunogen :

Purified recombinant fragment of MER expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. McGough N. Cummings JH. Proc Nutr Soc.2005, Nov,64(4):434-50. Review. ; 2. Allouache D. Gawande SR. Tubiana-Hulin M. et al. BMC Cancer. 2005, Nov 29,5:151. ; 3. Seguineau C. Soudant P. Moal J. et al. Lipids.2005, Sep,40(9): 931-9. ;

Type :

Monoclonal Antibody

Aliases :

MER; RP38; c-mer; MGC133349; MERTK