Mouse Monoclonal Antibody to Cytokeratin 5 | ProMab 20142 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to Cytokeratin 5

catalog :

20142

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3E2F1

The same clone is also sold as:

Santa Cruz Biotechnology: sc-81702
OriGene: AM06179SU-N
Abnova: MAB10726
Invitrogen: MA5-15347

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

20142

Title :

Mouse Monoclonal Antibody to Cytokeratin 5

Species :

Human

Clone :

3E2F1;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

CK5 (keratin 5) is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.

Immunogen :

Purified recombinant fragment of CK5 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Canedo-Patzi AM. Leon-Bojorge B. de Ortiz-Hidalgo C. Gac Med Mex. 2006, Jan-Feb, 142(1):59-66. Spanish. ; 2. Leibl S. Moinfar F. Am J Surg Pathol. 2006, Apr, 30(4):450-6. ;

Type :

Monoclonal Antibody

Aliases :

K5; DDD; EBS2; KRT5A; KRT5