Mouse Monoclonal Antibody to MYST1 | ProMab 20140 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MYST1

catalog :

20140

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8C4C4

The same clone is also sold as:

Santa Cruz Biotechnology: sc-81163
Abnova: MAB10823
Invitrogen: MA5-15345
OriGene: AM06177SU-N

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

Catalog :

20140

Title :

Mouse Monoclonal Antibody to MYST1

Species :

Human

Clone :

8C4C4;

lsotype :

Mouse IgG2b

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

MYST1 (MYST histone acetyltransferase 1, MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone

Immunogen :

Purified recombinant fragment of human MYST1 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000

References :

1. Sterner, D.E., et al. Microbiol. Mol. Biol 2000 Rev. 64: 435-459. ; 2. Neal, K.C., et al. Biochim. Biophys. 2000 Acta 1490: 170-174. ; 3. Akhtar, A., et al. EMBO 2001 Rep. 2: 113-118. ;

Type :

Monoclonal Antibody

MW :

53kDa

Aliases :

MOF; KAT8; hMOF