Mouse Monoclonal Antibody to CD31 | ProMab 20131 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CD31

catalog :

20131

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2F7B2

The same clone is also sold as:

Abnova: MAB10464
OriGene: AM06169SU-N
Santa Cruz Biotechnology: sc-81158
Invitrogen: MA5-15336

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

Catalog :

20131

Title :

Mouse Monoclonal Antibody to CD31

Species :

Human

Clone :

2F7B2;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells and platelets.CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).

Immunogen :

Purified recombinant fragment of human CD31 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000

References :

1. Mayr U et al. Circ Res 98:412-20 (2006). ; 2. Bingle L et al. Br J Cancer 94:101-7 (2006). ; 3. Wynne F et al. Reproduction 131:721-32 (2006). ;

Type :

Monoclonal Antibody

Aliases :

CD31; PECAM-1; PECAM1