Mouse Monoclonal Antibody to HER-2 | ProMab 20127 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to HER-2

catalog :

20127

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9B9D8

The same clone is also sold as:

Invitrogen: MA5-15332
OriGene: AM06167SU-N

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

20127

Title :

Mouse Monoclonal Antibody to HER-2

Species :

Human

Clone :

9B9D8;

lsotype :

Mouse IgG2b

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis

Immunogen :

Purified recombinant fragment of HER-2 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. RR Mehta, JH McDermott, TJ Hieken, et al. J. Clin. Oncol. 1998;16:2409 - 2416. ; 2. Hideko Y, Vered S, and Daniel F.H, et al. J. Clin. Oncol.2001;19:2334 - 2356. ; 3. Magali F, Kamel H, Cécile B, et al. Clinical Cancer Research. 2000;6:4745-4754. ;

Type :

Monoclonal Antibody

Aliases :

HER-2, C-erB-2, erbB-2