Mouse Monoclonal Antibody to C-Kit | ProMab 20121 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to C-Kit

catalog :

20121

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8D7

The same clone is also sold as:

Invitrogen: MA5-15327
OriGene: AM06162SU-N

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

20121

Title :

Mouse Monoclonal Antibody to C-Kit

Species :

Human

Clone :

8D7;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

C-kit (CD117, 145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

Immunogen :

Purified recombinant fragment of C-kit expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Mojica WD et.alHistopathology. 2005 Nov;47(5):517-22. ; 2. Tong WD et.alInt J Colorectal Dis. 2005 Jul;20(4):363-7. Epub 2005 Feb 2. ; 3. Nakai Y et.alBiochem Biophys Res Commun. 2005 Nov 11;337(1):289-96. ; ;

Type :

Monoclonal Antibody

MW :

145kDa

Aliases :

PBT; SCFR; C-Kit; CD117; KIT