Mouse Monoclonal Antibody to PR | ProMab 20107 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PR

catalog :

20107

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2F12B4

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

20107

Title :

Mouse Monoclonal Antibody to PR

Species :

Human

Clone :

2F12B4;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

PR(progesterone receptor), with 933-amino acid protein (about 110kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.

Immunogen :

Purified recombinant fragment of PR expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. McGuire, W.L., et al. 1986. Cancer.Surv.5:527-536. ; 2. Helena CD, Curt WB, Paul V,et al. 2000. J.Clin. Pathol. 53:201-205. ; 3. Wen, D.X., et al. 1994.Mol.Cell.Biol.14:8356-8364. ; 4. GM Clark, CK Osborne, WL McGuire.1984.J. Clin. Oncol., 2:1102-1109. ;

Type :

Monoclonal Antibody

Aliases :

PR; NR3C3; PGR