This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ProMab
product type :
antibody
product name :
Mouse Monoclonal Antibody to Desmin
catalog :
20094
quantity :
100µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10H7D2

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
product information
Catalog :
20094
Title :
Mouse Monoclonal Antibody to Desmin
Species :
Human
Clone :
10H7D2;
lsotype :
Mouse IgG1
Size :
100µl
Storage :
4?; -20? for long term storage
Description :
Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.
Immunogen :
Purified recombinant fragment of Desmin expressed in E. Coli.
Formulation :
Purified antibody in PBS containing 0.03% sodium azide.
Applications :
ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
References :
1. Felix R. Shardonofsky, Yassemi Capetanaki, and Aladin M. Boriek. Am J Physiol Lung Cell Mol Physiol, May 2006; 290: L890 - L896. ; 2. Xupei Huang, Jian Li, Dalton Foster. Experimental Biology and Medicine, Dec 2002; 227: 1039. ;
Type :
Monoclonal Antibody
Aliases :
Desmin
company information
ProMab
5221 Central Avenue, Suite 200
Richmond, CA 94804
info@promab.com
http://www.promab.com
1-866-339-0871
headquarters: USA