Mouse Monoclonal Antibody to SNCG (breast cancer-specific protein 1)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to SNCG (breast cancer-specific protein 1)

catalog :

20084

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1H10D2

The same clone is also sold as:

Santa Cruz Biotechnology: sc-65979
Invitrogen: MA5-15296
OriGene: AM06134PU-N
Abnova: MAB10408

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

20084

Title :

Mouse Monoclonal Antibody to SNCG (breast cancer-specific protein 1)

Species :

Human

Clone :

1H10D2;

lsotype :

Mouse IgG1

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

Immunogen :

Purified recombinant fragment of SNCG expressed in E. Coli.

Formulation :

Purified antibody in PBS containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Haiyan Liu, Wei Liu, Yinwei Wu. Cancer Res. 2005 Sep 1;65(17):7635-43. ; 2. Irina Surgucheva , Belinda McMahon , Andrei Surguchov. Cell Motil Cytoskeleton. 2006 May 26. ;

Type :

Monoclonal Antibody

Aliases :

SR; BCSG1