Mouse Monoclonal Antibody to Fibulin 5 | ProMab 20080 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to Fibulin 5

catalog :

20080

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3F8D5

The same clone is also sold as:

Abnova: MAB10643
OriGene: AM06131SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20080

Title :

Mouse Monoclonal Antibody to Fibulin 5

Species :

Human

Clone :

3F8D5;

lsotype :

Mouse Ig M

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

Fibulin 5(FBLN5), with 448-amino acid protein (about 50kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

Immunogen :

Purified recombinant fragment of Fibulin 5 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Wen Wang , Scott A. LeMaire, Li Chen. Surgery. 2005 Aug;138(2):352-9. ; 2. K. Kadoya, T. Sasaki, G. Kostka. Br J Dermatol. 2005 Sep;153(3):607-123. ; 3. Michael J. Lee, Nakshatra K. Roy, Jon E. Mogford. J Am Coll Surg. 2004 Sep;199(3):403-10. ;

Type :

Monoclonal Antibody

Aliases :

EVEC; UP50; ARMD3; DANCE