This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ProMab
product type :
antibody
product name :
Mouse Monoclonal Antibody to SNCA
catalog :
20077
quantity :
100µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B2D1

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
product information
Catalog :
20077
Title :
Mouse Monoclonal Antibody to SNCA
Species :
Human
Clone :
2B2D1;
Size :
100µl
Storage :
4?; -20? for long term storage
Description :
Alpha-synuclein (SNCA), with 140-amino acid protein (about 15kDa), belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Immunohistochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson's disease, Dementia with Lewy bodies and Multiple System Atrophy.
Immunogen :
Purified recombinant fragment of SNCA expressed in E. Coli. ; ;
Formulation :
Ascitic fluid containing 0.03% sodium azide.
Applications :
ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
References :
1. J. Johnson, S. M. Hague, M. Hanson. Neurology, Aug 2004; 63: 554 – 556 ; 2. Hong Tao Li, Xiao Jing Lin, Yuan Yuan Xie. Protein Pept Lett. 2006;13(4):385-90. ;
Type :
Monoclonal Antibody
Aliases :
PD1; NACP; PARK1; PARK4; MGC110988
company information
ProMab
5221 Central Avenue, Suite 200
Richmond, CA 94804
info@promab.com
http://www.promab.com
1-866-339-0871
headquarters: USA