Mouse Monoclonal Antibody to TGF beta1 | ProMab 20076 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to TGF beta1

catalog :

20076

quantity :

100µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4F9C10

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

20076

Title :

Mouse Monoclonal Antibody to TGF beta1

Species :

Human

Clone :

4F9C10;

lsotype :

Mouse IgG2a

Size :

100µl

Storage :

4?; -20? for long term storage

Description :

TGF beta(transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3,are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.

Immunogen :

Purified recombinant fragment of TGF beta1 expressed in E. Coli. ; ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Delphine Boche, Colm Cunningham, Fabian Docagne. Neurobiol Dis. 2006 Feb 27 ; 2. Shizuya Saika. Lab Invest. 2006 Feb;86(2):106-15 ;

Type :

Monoclonal Antibody

Aliases :

CED; DPD1; TGFB; TGFbeta; TGFB1